Information
Key Notes
- Journal(s): 16
- Text Book(s): 1
- PhD: Current - 5 Awarded - 8
- Event(s) Organized: Workshop - 3
17
PUBLICATIONS13
DOCTORAL STUDENTS5
PROJECTS1
PATENTResearch Areas
Medicinal Chemistry
Organic Synthesis, Development of Gene Delivery Vectors
EDUCATION QUALIFICATION
| Degree | Institute | Year |
|---|---|---|
| Doctor of Philosophy | Indian Institute of Chemical Technology (affiliated to OU) | 2002 |
| Master of Science | NITW (Formerly RECW) | 1996 |
| Bachelor of Science | Acharya Nagarjuna University | 1994 |
COURSES HANDLED
| Course | L-T-P | Credit | Degree Level |
|---|---|---|---|
| Organic Reactions and Mechanism(CY16007) | 3-0-0 | 3 | UG, PG |
| Engineering Chemistry(CY1161) | 3-0-2 | 4 | UG |
| Bio-organic Chemistry(CY16024) | 3-0-0 | 3 | UG, PG |
| Organic Chemistry Laboratory(CY2204) | 0-1-2 | 2 | UG |
| Chemistry of Natural Products(CY5104) | 3-0-0 | 3 | PG |
| Engineering Chemistry(CY185) | 3-0-2 | 4 | UG |
| Organic Chemistry - I(CY3102) | 3-0-2 | 4 | UG |
| Drug Development and Delivery Systems(CY5161) | 3-0-0 | 3 | PG |
| Chemistry of Biomolecules(CY5172) | 3-0-0 | 3 | PG |
RESEARCH IDs
ORC ID
PUBLICATIONS
Journal(s)
Design and Synthesis Of Pyrrolo[2,3-d]Pyrimidine Linked Diazospiro And Piperazine – Piperidine Libraries As Anticancer Agents,
By Sridhar Guda, Srilakshmi V Patri,* Krishna Reddy.V . Vishnu Thumma, Santosh Kumar Guru.,
Spinger Nature,
Medicinal Chemistry Research,
vol.,
pp.,
2026
New α-Tocopherol - Isoxazole Hybrids: Synthesis, In Vitro Anticancer and Antioxidant Evaluation, and Molecular Docking Insights. ,
By Srilakshmi.V. Patri, Pallavi Hanchate, Akash Kumar A, Akanksha Ashok Sangolkar, Shruthi Chilumula,Vasikaran A,,
Wiley,
ChemistrySelect ,
vol.10 (46).,
pp.,
2026
Synthesis of Small Molecule 1,2,4-Triazole Hybrids as Anticancer Agents Against HepG2 and HeLa Cell Lines. ,
By Sridhar Guda, Srilakshmi V. Patri, Krishna Reddy V, Shruthilaya Chilumula, Swetha Medchalmi, Shyam Perugu. ,
Wiley,
ChemistrySelect , ,
vol.,
pp.,
2026
Influence of structural modifications in synthetic vectors of lipid adjuvants in mRNA vaccine delivery. ,
By Srilakshmi V. Patri*, Shruthilaya Chilumula, Pallavi Hanchatea, Srujan Marepally*.,
Royal Society of Chemistry,
Biomaterials Science, ,
vol.13,
pp. 4952 – 4969. ,
2025
Synthesis, biological evaluation and molecular docking studies of new hybrids of α-tocopherol and aryl/heterocyclic group through 1,2,3-triazole spacer. ,
By Pallavi Hanchate, Shyam Perugu, Rama Krishna Kadiyam, Shireesha Manturthi, Akash Kumar and SrilakshmiV.Patri. ,
Spinger Nature,
Journal of the Iranian Chemical Society,
vol.21,
pp.1509–1518,
2024
Development of Tris‐(triazolyl)‐ s– triazine Linker‐Based Cationic Amphiphiles: Stability and Gene Delivery Applications. ,
By Shireesha Manturthi, Kumar Pranav Narayan, Kumar Pranav Narayan and Srilakshmi V Patri. ,
Wiley,
ChemistrySelect ,
vol.8(46). DOI: 10.1002/slct.202302649,
pp.,
2023
Effect of hydrophobic domain modification on the structure-activity relationship of DC Cholesterol based cationic lipids for efficient gene delivery,
By Hithavani Rapaka,, Mallikarjun Gosangi, Shireesha Manturthi, Brijesh Lohchania, Srujan Marepally, Srilakshmi V Patri,
ACS,
ACS-Applied Biomaterials ,
vol.1489-1500,
pp.5, 4,
2022
Green Approach to Synthesize Nano Zinc Oxide via Moringa oleifera Leaves for Enhanced Anti-oxidant, Anti-acne and Anti-bacterial Properties for Health & Wellness Applications,
By Nitesh Bhalla, Nitin Narayan Ingle, Athira Jayaprakash, Hiral Patel, Srilakshmi V Patri, Haranath Divi.,
Elsevier,
Arabian Journal of Chemistry,
vol.104506,
pp.16(1),
2022
Cimetidine-Based Cationic Amphiphiles for In-vitro Gene Delivery Targetable to Colon Cancer,
By Shireesha Manturthi, Dwaipayan Bhattacharya, Kalyani Rajesh Sakhare, Kumar Pranav Narayan, Srilakshmi V. Patri,
ACS,
ACS Omega,
vol.31388–31402,
pp.7 (35),
2022
Nicotinic Acid-Based Cationic Vectors for Efficient Gene Delivery to Glioblastoma Cells,
By Shireesha Manturthi, Dwaipayan Bhattacharya, Kalyani Rajesh Sakhare, Kumar Pranav Narayan, Srilakshmi V. Patri,
RSC,
New J. Chem,
vol.20886-20899,
pp.46,
2022
Dicationic amphiphiles bearing an amino acid head group with long-chain hydrophobic tail for efficient in vitro gene delivery,
By Shireesha Manturthi, Kumar Pranav Narayan, Srilakshmi V. Patri,
RSC,
RSC ADVANCES,
vol.33264-33275,
pp.12,
2022
Effect of methylation in the hydrophilic domain of Tocopherol based amino lipids on their nucleic acid delivery properties,
By Hithavani Rapaka,, Mallikarjun Gosangi, Shireesha Manturthi, Brijesh Lohchania, Srujan Marepally, Srilakshmi V Patri,
ACS,
ACS Omega,
vol.15396-15403,
pp.7, 18,
2022
A facile approach to fabricate and embed multifunctional nano ZnO into soap matrix and liquid cleansing products for enhanced antibacterial and photostability for health and hygiene applications,
By Nitesh Bhalla, Nitin Ingle, Hiral Patel, Athira Jayaprakash, Srilakshmi V. Patri, Ajeet Kaushik, D. Haranath,
Elsevier,
Arabian Journal of Chemistry,
vol.103862,
pp.15,
2022
Phytochemical analysis of Moringa Oleifera leaves extracts by GC-MS and free radical scavenging potency for industrial applications,
By Nitesh Bhalla, Nitin Ingle, Srilakshmi V. Patri, Haranath,
SCIENCE DIRECT ,
Saudi Journal of Biological Sciences,
vol.6915–6928,
pp.28(12),
2021
α-Tocopherol-Conjugated, Open Chain Sugar-Mimicking Cationic Lipids: Design, Synthesis and In–Vitro Gene Transfection Properties,
By Venkatesh Ravula, Venkanna Muripiti,Shireesha Manthurthi, Srilakshmi V. Patri,
Wiley-VCH,
Chemistry Select,
vol.13025-13033,
pp.6, 46,
2021
Gemini Lipopeptide Bearing an Ultrashort Peptide for Enhanced Transfection Efficiency and Cancer-cell-specific Cytotoxicity,
By Ravula, Venkatesh; Lo, Yu-Lun; Wang, Li-Fang; Patri Srilakshmi,
ACS,
ACS Omega,
vol.22955–22968,
pp.6, 35,
2021
Text Book(s)
Intermediate Text Book
By Editor:Prof. M, Vi,ljul1t1,a
Prof. B. Manohar
Prof. P.V. Srilakshmi
(Published by: Telangana Board of Intermediate Education),
Text Book,
2026
Patent(s)
PROCESS FOR PREPARING FARNESOL-BASED CATIONIC LIPIDS FOR CARRYING NUCLEIC ACIDS IN TO DESIRED CELL LINES (AU 2021106376 A4)
PROJECT / CONSULTANCY
A New Class of Blood-Brain-Barrier Crossing Fluorescence-based Nanotheranostic Systems for Neurodegenerative Diseases
Role:
Co-Principal Investigator
Type: SPARC Project
Sponsor: DST
Project Cost (INR): 4464000
Date of Commencement: 01-04-2024 Date of Completion: 31-03-2026
Duration: 24 Months
Status: Completed
Type: SPARC Project
Sponsor: DST
Project Cost (INR): 4464000
Date of Commencement: 01-04-2024 Date of Completion: 31-03-2026
Duration: 24 Months
Status: Completed
Heterocyclic Based Peptidomimetics for non-viral Gene Delivery
Role:
Principal Investigator
Type: Research
Sponsor: SERB-DST
Project Cost (INR): 4000000
Date of Commencement: 22-03-2019 Date of Completion: 21-03-2023
Duration: 49 Months
Status: Completed
Type: Research
Sponsor: SERB-DST
Project Cost (INR): 4000000
Date of Commencement: 22-03-2019 Date of Completion: 21-03-2023
Duration: 49 Months
Status: Completed
Development of Pyrazole, Triazole and Tetrazole Based Novel Cationic lipids for Targeting Non-viral Gene Delivery to Tumors
Role:
Principal Investigator
Type: Research
Sponsor: SERB-DST
Project Cost (INR): 3200000
Date of Commencement: 07-02-2013 Date of Completion: 06-02-2015
Duration: 25 Months
Status: Completed
Type: Research
Sponsor: SERB-DST
Project Cost (INR): 3200000
Date of Commencement: 07-02-2013 Date of Completion: 06-02-2015
Duration: 25 Months
Status: Completed
Development of Benzoxazole, Benzthiazole and Benzimidazoles Based Novel Cationic Amphiphiles for Non-Viral Gene Delivery Targeting to Tumors
Role:
Principal Investigator
Type: Research
Sponsor: Fast-track Proposal Your Scientist-DST
Project Cost (INR): 1920000
Date of Commencement: 20-03-2010 Date of Completion: 19-03-2013
Duration: 37 Months
Status: Completed
Type: Research
Sponsor: Fast-track Proposal Your Scientist-DST
Project Cost (INR): 1920000
Date of Commencement: 20-03-2010 Date of Completion: 19-03-2013
Duration: 37 Months
Status: Completed
Rational Design and Synthesis of Dimerizable and Targetable Cationic Peptide Amphiphiles for Non-viral Gene Delivery
Role:
Principal Investigator
Type: Research
Sponsor: CSIR
Project Cost (INR): 1000000
Date of Commencement: 16-06-2007 Date of Completion: 15-06-2010
Duration: 37 Months
Status: Completed
Type: Research
Sponsor: CSIR
Project Cost (INR): 1000000
Date of Commencement: 16-06-2007 Date of Completion: 15-06-2010
Duration: 37 Months
Status: Completed
RESEARCH FELLOWS / PhD STUDENTS
Current PhD Students
Akash Kumar
Area of Research:
Non-viral Gene Delivery Vectors
Pallavi H
Area of Research:
Tocopherol based Conjugates for Biological Applications
Shrutilaya Chilumula
Area of Research:
Non-Viral Gene Delivery Vectors
Sridhar Guda
Area of Research:
Synthesis of biologically active organic molecules
Vasikaran A
Area of Research:
Prostaglandin and Lysine Head group based Nanofibers
Previous PhD Students
Shirisha Manturthi
(2023)
Area of Research:
Non-viral Gene Delivery Vectors
Nitesh Balla
(2023)
Area of Research:
Green approaches to Fabricate Nano ZnO for Industrial Applic
Venkatesh Ravula
(2022)
Area of Research:
Non-Viral Gene Delivery Vectors
Hithavani Rapaka
(2022)
Area of Research:
Non-viral gene Delivery Vectors
Venkanna Muripiti
(2018)
Area of Research:
Non-Viral Gene Delivery Vectors
Mallikarjun Gosangi
(2017)
Area of Research:
Non-Viral Gene Delivery
Amarnath Velidandi
(2013)
Area of Research:
Porphyrins and Heterocyclic Compound for Biological Applicat
Bhavani Kedika
(2011)
Area of Research:
Non-Viral Gene Delivery
CONFERENCE / WORKSHOP / SYMPOSIUM / SHORT TERM COURSE / FACULTY DEVELOPMENT PROGRAMME / GIAN
“Development of Drug/Gene Delivery Vectors”
13-May-2022
→
14-May-2022
Event Type:
Workshop
Role: Coordinator
Funding Agency: Department of Science and Technology
Role: Coordinator
Funding Agency: Department of Science and Technology
Nanotheranostics-II: A Step Towards Translational Medicine (16th – 21st February, 2026)
16-Feb-2026
→
21-Feb-2026
Event Type:
Workshop
Role: Coordinator
Funding Agency: SPARC
Role: Coordinator
Funding Agency: SPARC
“Nanotheranostics: From Basic Principles to Clinical Utility” 28th January – 4th February, 2025
28-Jan-2025
→
04-Feb-2025
Event Type:
Workshop
Role: Coordinator
Funding Agency: SPARC
Role: Coordinator
Funding Agency: SPARC
ADDITIONAL RESPONSIBILITIES
- INstitute Plagiarism Committee Chairperson (November, 2025 - July, 2026)
- Associate Dean Academic-Industry Connect (September, 2025 - June, 2026)
- Internal Complaints Committee Chairperson (July, 2025 - July, 2026)
- Institute Research Development Committee Member (August, 2023 - July, 2026)
- Head, Central Research Instrumentation Facility (July, 2023 - June, 2025)
- Head Department of Chemistry (August, 2018 - August, 2020)
Last updated on July 10, 2026