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Prof. P Venkata Sri Laxmi

Professor

Department of Chemistry

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Information

Room No: 511 +91-870-2462672 patrisrilakshmi@nitw.ac.in Bio Sketch

    Key Notes

    • Journal(s): 10
    • PhD: Current - 5  Awarded - 8

    10

    PUBLICATIONS

    13

    DOCTORAL STUDENTS

    5

    PROJECTS

    1

    PATENT

    Research Areas

    Medicinal Chemistry
    Organic Synthesis, Development of Gene Delivery Vectors
    EDUCATION QUALIFICATION
    Degree Institute Year
    Doctor of Philosophy Indian Institute of Chemical Technology (affiliated to OU) 2002
    Master of Science NITW (Formerly RECW) 1996
    Bachelor of Science Acharya Nagarjuna University 1994
    COURSES HANDLED
    Course L-T-P Credit Degree Level
    Engineering Chemistry(CY1161) 3-0-2 4 UG
    Organic Reactions and Mechanism(CY16007) 3-0-0 3 UG, PG
    Bio-organic Chemistry(CY16024) 3-0-0 3 UG, PG
    Organic Chemistry Laboratory(CY2204) 0-1-2 2 UG
    Chemistry of Natural Products(CY5104) 3-0-0 3 PG
    Engineering Chemistry(CY185) 3-0-2 4 UG
    Organic Chemistry - I(CY3102) 3-0-2 4 UG
    Chemistry of Biomolecules(CY5172) 3-0-0 3 PG
    Drug Development and Delivery Systems(CY5161) 3-0-0 3 PG
    RESEARCH IDs
    ORCID
    ORC ID
    PUBLICATIONS
    Journal(s)
    Green Approach to Synthesize Nano Zinc Oxide via Moringa oleifera Leaves for Enhanced Anti-oxidant, Anti-acne and Anti-bacterial Properties for Health & Wellness Applications, By Nitesh Bhalla, Nitin Narayan Ingle, Athira Jayaprakash, Hiral Patel, Srilakshmi V Patri, Haranath Divi., Elsevier, Arabian Journal of Chemistry, vol.104506, pp.16(1), 2022
    Cimetidine-Based Cationic Amphiphiles for In-vitro Gene Delivery Targetable to Colon Cancer, By Shireesha Manturthi, Dwaipayan Bhattacharya, Kalyani Rajesh Sakhare, Kumar Pranav Narayan, Srilakshmi V. Patri, ACS, ACS Omega, vol.31388–31402, pp.7 (35), 2022
    Nicotinic Acid-Based Cationic Vectors for Efficient Gene Delivery to Glioblastoma Cells, By Shireesha Manturthi, Dwaipayan Bhattacharya, Kalyani Rajesh Sakhare, Kumar Pranav Narayan, Srilakshmi V. Patri, RSC, New J. Chem, vol.20886-20899, pp.46, 2022
    Dicationic amphiphiles bearing an amino acid head group with long-chain hydrophobic tail for efficient in vitro gene delivery, By Shireesha Manturthi, Kumar Pranav Narayan, Srilakshmi V. Patri, RSC, RSC ADVANCES, vol.33264-33275, pp.12, 2022
    Effect of methylation in the hydrophilic domain of Tocopherol based amino lipids on their nucleic acid delivery properties, By Hithavani Rapaka,, Mallikarjun Gosangi, Shireesha Manturthi, Brijesh Lohchania, Srujan Marepally, Srilakshmi V Patri, ACS, ACS Omega, vol.15396-15403, pp.7, 18, 2022
    A facile approach to fabricate and embed multifunctional nano ZnO into soap matrix and liquid cleansing products for enhanced antibacterial and photostability for health and hygiene applications, By Nitesh Bhalla, Nitin Ingle, Hiral Patel, Athira Jayaprakash, Srilakshmi V. Patri, Ajeet Kaushik, D. Haranath, Elsevier, Arabian Journal of Chemistry, vol.103862, pp.15, 2022
    Effect of hydrophobic domain modification on the structure-activity relationship of DC Cholesterol based cationic lipids for efficient gene delivery, By Hithavani Rapaka,, Mallikarjun Gosangi, Shireesha Manturthi, Brijesh Lohchania, Srujan Marepally, Srilakshmi V Patri, ACS, ACS-Applied Biomaterials , vol.1489-1500, pp.5, 4, 2022
    Gemini Lipopeptide Bearing an Ultrashort Peptide for Enhanced Transfection Efficiency and Cancer-cell-specific Cytotoxicity, By Ravula, Venkatesh; Lo, Yu-Lun; Wang, Li-Fang; Patri Srilakshmi, ACS, ACS Omega, vol.22955–22968, pp.6, 35, 2021
    α-Tocopherol-Conjugated, Open Chain Sugar-Mimicking Cationic Lipids: Design, Synthesis and In–Vitro Gene Transfection Properties, By Venkatesh Ravula, Venkanna Muripiti,Shireesha Manthurthi, Srilakshmi V. Patri, Wiley-VCH, Chemistry Select, vol.13025-13033, pp.6, 46, 2021
    Phytochemical analysis of Moringa Oleifera leaves extracts by GC-MS and free radical scavenging potency for industrial applications, By Nitesh Bhalla, Nitin Ingle, Srilakshmi V. Patri, Haranath, SCIENCE DIRECT , Saudi Journal of Biological Sciences, vol.6915–6928, pp.28(12), 2021
    Patent(s)
    PROCESS FOR PREPARING FARNESOL-BASED CATIONIC LIPIDS FOR CARRYING NUCLEIC ACIDS IN TO DESIRED CELL LINES (AU 2021106376 A4)
    PROJECT / CONSULTANCY
    A New Class of Blood-Brain-Barrier Crossing Fluorescence-based Nanotheranostic Systems for Neurodegenerative Diseases
    Role: Co-Principal Investigator
    Type: SPARC Project
    Sponsor: DST
    Project Cost (INR): 4464000
    Date of Commencement: 01-04-2024  
    Duration: 23 Months
    Status: Ongoing
    Heterocyclic Based Peptidomimetics for non-viral Gene Delivery
    Role: Principal Investigator
    Type: Research
    Sponsor: SERB-DST
    Project Cost (INR): 4000000
    Date of Commencement: 22-03-2019   Date of Completion: 21-03-2023
    Duration: 48 Months
    Status: Completed
    Development of Pyrazole, Triazole and Tetrazole Based Novel Cationic lipids for Targeting Non-viral Gene Delivery to Tumors
    Role: Principal Investigator
    Type: Research
    Sponsor: SERB-DST
    Project Cost (INR): 3200000
    Date of Commencement: 07-02-2013   Date of Completion: 06-02-2015
    Duration: 24 Months
    Status: Completed
    Development of Benzoxazole, Benzthiazole and Benzimidazoles Based Novel Cationic Amphiphiles for Non-Viral Gene Delivery Targeting to Tumors
    Role: Principal Investigator
    Type: Research
    Sponsor: Fast-track Proposal Your Scientist-DST
    Project Cost (INR): 1920000
    Date of Commencement: 20-03-2010   Date of Completion: 19-03-2013
    Duration: 36 Months
    Status: Completed
    Rational Design and Synthesis of Dimerizable and Targetable Cationic Peptide Amphiphiles for Non-viral Gene Delivery
    Role: Principal Investigator
    Type: Research
    Sponsor: CSIR
    Project Cost (INR): 1000000
    Date of Commencement: 16-06-2007   Date of Completion: 15-06-2010
    Duration: 36 Months
    Status: Completed
    RESEARCH FELLOWS / PhD STUDENTS
    Current PhD Students
    Akash Kumar
    Area of Research: Non-viral Gene Delivery Vectors
    Pallavi H
    Area of Research: Tocopherol based Conjugates for Biological Applications
    Shrutilaya Chilumula
    Area of Research: Non-Viral Gene Delivery Vectors
    Sridhar Guda
    Area of Research: Synthesis of biologically active organic molecules
    Vasikaran A
    Area of Research: Prostaglandin and Lysine Head group based Nanofibers
    Previous PhD Students
    Shirisha Manturthi (2023)
    Area of Research: Non-viral Gene Delivery Vectors
    Nitesh Balla (2023)
    Area of Research: Green approaches to Fabricate Nano ZnO for Industrial Applic
    Venkatesh Ravula (2022)
    Area of Research: Non-Viral Gene Delivery Vectors
    Hithavani Rapaka (2022)
    Area of Research: Non-viral gene Delivery Vectors
    Venkanna Muripiti (2018)
    Area of Research: Non-Viral Gene Delivery Vectors
    Mallikarjun Gosangi (2017)
    Area of Research: Non-Viral Gene Delivery
    Amarnath Velidandi (2013)
    Area of Research: Porphyrins and Heterocyclic Compound for Biological Applicat
    Bhavani Kedika (2011)
    Area of Research: Non-Viral Gene Delivery
    CONFERENCE / WORKSHOP / SYMPOSIUM / SHORT TERM COURSE / FACULTY DEVELOPMENT PROGRAMME
    ADDITIONAL RESPONSIBILITIES
    •  Internal Complaints Committee Chairperson (Continuing from July, 2025)
    •  Head, Central Research Instrumentation Facility (July, 2023 - June, 2025)
     Last updated on August 1, 2025