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Prof. D Kashinath

PhD (Indian Institute of Technology Bombay, Powai, Mumbai)

Professor

Department of Chemistry

Room No: 401   +91-870-2462677
kashinath@nitw.ac.in
8332969502 Edit Profile Bio Sketch

Research Areas

 Acetyl and Butyrylcholinesterase inhibitors ((Alzheimer's)  

 Alpha-Glucosidase inhibitors (Type-2 diabetes) 

 Deep Eutectic Solvents and Ionic liquids as reaction media 

 Directed C-H activation 

 Green Chemistry (Metal-free reactions) 

 Metal-free C-C, C-N, C-O bond formation 

 Synthesis of Bioactive compounds 

  • Courses Handled
  • Research IDs
  • Selected Publications
  • Project/Consultancy
  • Current PhD Students
  • Awards and Accolades
  • Additional Responsibilities
  • Organic Preparations Laboratory(CY5106)
  • Medicinal Chemistry(CY5113)
  • Stereo Selective Synthesis(CY5102)
  • Chemistry for Civil Engineers(CY183)
  • Engineering Chemistry(CY1161)
  • Organic Chemistry Laboratory(CYI302)
  • Organic Chemistry - I(CY3102)
  • Organic Chemistry - I(CY2102)
  • Engineering Chemistry(CY185)
  • General Chemistry-II(CYI151)
  • Seminar - I(CYI348)
  • Organic Chemistry Laboratory - II(CY4156)
  • Organic Reagents and Name Reactions(CY4161)
  • Mini Project Work(CYI399)
  • Organic Synthesis(CY5101)
  • Seminar - II(CY5148)
  • Organic Chemistry Laboratory - I(CY4107)
  • Dissertation Work(CY5199)
  • Comprehensive Viva-voce(CY5197)
  • Seminar - I(CY4198)
  • Chemistry Laboratory(CY182)
  • Industrial Organic Chemistry(CY181)
  • ORC ID: 0000-0002-2509-0386
  • ISI Researcher ID: https://nitw.irins.org/profile/66880
  • Google Scholar ID: https://scholar.google.co.in/citations?user=09x3tKcAAAAJ&hl=en


  • One-Pot Synthesis of Functionalized Carbazoles and β-Carbolines via Diethyl Azodicarboxylate Mediated Dehydrogenative Aromatization in Deep Eutectic Solvent, By Thangellapally Shirisha, Subir Majhi, Prof. Dhurke Kashinath, Wiley Interscience, ChemistrySelect, vol.9, pp.e202401275, 2024
  • Metal-free C(sp3)-H functionalization (C-C and C-N bond formation) of 1,2,3,4-tetrahydroacridines using Deep Eutectic solvent as catalyst and reaction medium, By Thangellapally Shirisha, Subir Majhi, Balasubramanyan Sridhar, and Dhurke Kashinath, Royal Society of Chemistry, Organic & Biomolecular Chemistry , vol.22, pp.1434-1440, 2024
  • Metal-free synthesis of functionalized tacrine derivatives and their evaluation for acetyl/butyrylcholinesterase and α-glucosidase inhibition, By Thangellapally Shirisha, Subir Majhi, Kalivatharan Divakar, and Dhurke Kashinath, Royal Society of Chemistry, Organic & Biomolecular Chemistry , vol.22, pp.790-804, 2024
  • Synthesis of 2-styryl-quinazoline and 3-styryl-quinoxaline based sulfonate esters via sp3 C–H activation and their evaluation for α-glucosidase inhibition, By Neeli Satyanarayana, Boddu Ramya Sree, Kota Sathish, Sakkani Nagaraju, Kalivarathan Divakar, Ravinder Pawar, Thangellapally Shirisha, and Dhurke Kashinath, Royal Society of Chemistry, New Journal of Chemistry, vol.59, pp.1599, 2022
  • Metal-free, one-pot synthesis of 2-styrylquinolines via Friedländer annulation and sp 3 C–H activation using 1, 3-dimethylurea and l-tartaric acid (3: 1) as a deep eutectic solvent, By Neeli Satyanarayana, Kota Sathish, Sakkani Nagaraju, Ravinder Pawar, Mohmmad Faizan, Murgan Arumugavel, Thangellapally Shirisha, Dhurke Kashinath, Royal Society of Chemistry, New Journal of Chemistry, vol.46, pp.1637-1, 2022
  • Applications of 3,5‐Dialkyl‐4‐nitroisoxazoles and Their Derivatives in Organic Synthesis, By Sakkani Nagaraju, Kota Sathish, Dhurke Kashinath, Wiley InterScience, ChemistrySelect, vol.6, pp.7736, 2021
  • Synthesis of 4H-chromene-isoxazole hybrids via ortho-hydroxy directing cyclization of isoxazole-styrenes and Michael addition of imino-chromenes in aqueous medium, By Sakkani Nagaraju, Kota Sathish, Dhurke Kashinath, Wiley InterScience, Journal of Heterocyclic Chemistry, vol.58, pp.1252-1258, 2021
  • Synthesis of 3-ethynyl-3-hydroxy-2-oxindoles and 3-hydroxy-3-(indol-3-yl) indolin-2-ones using CuWO4 nanoparticles as recyclable heterogeneous catalyst in aqueous medium, By B Paplal, K Sathish, S Nagaraju, D Kashinath, Elsevier, Catalysis Communications, vol.135, pp.105874, 2020
  • Regioselective synthesis of spiro isoxazole‐oxindole‐tetrahydrothiophene hybrids via cascade reactions under catalyst‐free conditions, By S Nagaraju, K Sathish, N Satyanarayana, B Paplal, D Kashinath, Wiley InterScience, Journal of Heterocyclic Chemistry, vol.57, pp.469-476, 2020
  • 3-Hydroxy-3-((3-methyl-4-nitroisoxazol-5-yl)methyl)indolin-2-one as a versatile intermediate for retro-Henry and Friedel–Crafts alkylation reactions in aqueous medium, By Sakkani Nagaraju , Kota Sathish , Banoth Paplal , Neeli Satyanarayana and Dhurke Kashinath , Royal Society of Chemistry, New Journal of Chemistry, vol.43, pp.14045-14050, 2019

4. Synergistic effect of phosphonium, ammonium based ionic liquid and nano lubricants on the tribological and rheological properties

  • Role Principal Investigator
  • Type Research
  • Sponsor DST (SERB)
  • Duration 23 Months
  • Project Cost (INR) 1764000
  • Status Completed

3. Synthesis of novel 1-(phenyl(phenylamino)methyl)naphthalene-2-ol based chiral catalysts and their applications to asymmetric organic transformations (C-H activation)

  • Role Principal Investigator
  • Type Research
  • Sponsor DST (SERB)
  • Duration 35 Months
  • Project Cost (INR) 3400000
  • Status Completed

2. Design and synthesis of (-)-kaitocephalin derivatives and their pharmacological evaluation as ionotropic glutamate receptor (iGluRs) antagonists

  • Role Principal Investigator
  • Type Research
  • Sponsor DST (SERB)
  • Duration 35 Months
  • Project Cost (INR) 2300000
  • Status Completed

1. Discovery of Inhibitors of System Xc¯ Transporter, a Novel Therapeutic Target for Glutamate-Mediated Excitotoxicity and Epileptogenesis

  • Role Co-Principal Investigator
  • Type Research
  • Sponsor DBT (Neuroscience Taskforce)
  • Duration 23 Months
  • Project Cost (INR) 1900000
  • Status Completed


Ankita Parida

  • Area of Research: Development of Synthetic methods

Bhuvaneshwari M

  • Area of Research: Development of synthetic methods for nitrogen and sulfur containing heterocyclic molecules

Karunakar Rudra

  • Area of Research: Development of Synthetic Methods for Biologically Active Molecules

N. Jayaram

  • Area of Research: Development of analytical methods for the xenotoxic impurities in active pharmaceuitcal ingradients

Rajesh G

  • Area of Research: Development of synthetic methods using non-conventional reagents

Subir Majhi

  • Area of Research: C-H bond activation reactions

Varukolu Shanker

  • Area of Research: Development of synthetic methods for bioactive compounds
  • Best Review Article Award from IIT Bombay for
  • Junior Research Fellow
  • Senior Research Fellow,
  • Head, Department of Chemistry (August, 2022 - June, 2024)
  • Head of the Department (June, 2022 - June, 2024)
  • Associate Dean (Central Library) (October, 2016 - December, 2018)
  • Faulty-in-Charge (LC-HRMS Instrument) (July, 2015 - January, 2024)