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Prof. K Hari Prasad

Associate Professor

Department of Chemistry

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Information

Room No: 406 MME & Science Block +91-870-2462679 harikokatla@nitw.ac.in Bio Sketch

    Key Notes

    • Journal(s): 27
    • Conference(s): 3
    • Book Chapter(s): 1
    • PhD: Current - 12  Awarded - 4

    31

    PUBLICATIONS

    16

    DOCTORAL STUDENTS

    5

    PROJECTS

    1

    PATENT

    Research Areas

    Organic Synthesis, Carbohydrate and Medicinal Chemistry
    EDUCATION QUALIFICATION
    Degree Institute Year
    Doctor of Philosophy IIT Kanpur 2010
    Master of Science University of Hyderabad 2004
    Bachelor of Science PG College of Saifabad, Osmania University 2002
    COURSES HANDLED
    Course L-T-P Credit Degree Level
    General Chemistry(CY2101) 3-0-0 3 UG
    Chemistry for Civil Engineers(CY183) 3-0-0 3 UG
    Engineering Chemistry(CY1161) 3-0-2 4 UG
    Photochemistry and Pericyclic reactions(CY16002) 4-0-0 4 UG, PG
    Green Chemistry(CY17044) 3-0-0 3 UG, PG
    Photochemistry and Pericyclic Reactions(CY4153) 3-0-0 3 PG
    Organic Chemistry - I(CY3102) 3-0-2 4 UG
    General Chemistry-I(CYI101) 3-0-0 3 UG
    General Chemistry - II(CYB201) 3-0-2 4 UG
    Stereo Selective Synthesis(CY5102) 3-0-0 3 PG
    Engineering Chemistry(CY185) 3-0-2 4 UG
    Carbohydrate Chemistry(CY5163) 3-0-0 3 PG
    Green Chemistry(CY5111) 3-0-0 3 PG
    Chemistry of Biomolecules(CY5172) 3-0-0 3 PG
    RESEARCH IDs
    ORCID
    ORC ID
    Scopus
    SCOPUS ID
    Google Scholar
    Google Scholar ID
    PUBLICATIONS
    Journal(s)
    Rongalite as a mild reductant for solvent-assisted dechlorination of 3,3-dichlorooxindoles to 3-chloro-2-oxindoles and 2-oxindoles, By Jalagam Swathi, Hari Prasad Kokatla, Sivaparwathi Golla and Nagaraju Naddi, RSC, Organic & Biomolecular Chemistry, vol., pp., 2026
    Chemoselective Reduction of α-Keto Aldehydes by Rongalite in Water: A Metal and Hydride Free Approach, By Madhu Inapanuri, Hari Prasad Kokatla, Rambabu Kandukuri and Neetika Singh, RSC, Organic & Biomolecular Chemistry, vol., pp., 2025
    One-Pot Aminomethylation of Heteroarenes by Rongalite as In Situ C1 Source, By Sanjeeva Thunga, Neetika Singh, Naveenkumar Anugu, Hari Prasad Kokatla, ACS, The Journal of Organic Chemistry, vol.89, pp.18649–18653, 2024
    Rongalite as a Methylene Surrogate: Synthesis of Heterodiarylmethanes via C(sp2)-H Functionalization, By Sanjeeva Thunga, Madhu Inapanuri, Neetika Singh, Hari Prasad Kokatla, ACS, The Journal of Organic Chemistry, vol.89, pp.18313–18321, 2024
    Rongalite induced metal-free C (sp 2)–H functionalization of indoles: direct access to 3-(sulfonylmethyl) indoles, By Sanjeeva Thunga, Neetika Singh, Madhu Inapanuri, Hari Prasad Kokatla, RSC, Organic & Biomolecular Chemistry, vol.22, pp. 8787-8792, 2024
    N-Oxide-Induced Ugi Reaction: A Rapid Access to Quinoline-C2-amino Amides via Deoxygenative C(sp2)–H Functionalization, By Naveenkumar Anugu, Sanjeeva Thunga, Soumya Poshala, Hari Prasad Kokatla, American Chemical Society, The Journal of Organic Chemistry , vol.87, pp.10435, 2022
    Rongalite-Mediated Transition Metal-and Hydride-Free Chemoselective Reduction of α-Keto Esters and α-Keto Amides, By Sivaparwathi Golla, Hari Prasad Kokatla, American Chemical Society, The Journal of Organic Chemistry , vol.87, pp.9915, 2022
    Transition metal-free functionalization of 2-oxindoles via sequential aldol and reductive aldol reactions using rongalite as a C1 reagent., By Sivaparwathi Golla, Swathi Jalagam, Soumya Poshala, Hari Prasad Kokatla, Royal Society of Chemistry, Organic and Biomolecular Chemistry, vol.20, pp.4926, 2022
    Rongalite-induced transition-metal and hydride-free reductive aldol reaction: a rapid access to 3,3′-disubstituted oxindoles and its mechanistic studies., By Sivaparwathi Golla, Naveenkumar Anugu,Swathi Jalagam, Hari Prasad Kokatla, Royal Society of Chemistry, Organic and Biomolecular Chemistry, vol.20, pp.808, 2022
    Iodine Catalyzed C2-H Formamidation of Quinoline N-Oxides using Isocyanides: A Metal-Free Approach., By Naveenkumar Anugu, Sanjeeva Thunga, Sivaparwathi Golla, Hari Prasad Kokatla, Wiley, Advaned Synthesis & Catalysis, vol.364, pp.149, 2022
    An Efficient Pd(II)-(2-aminonicotinaldehyde) Complex As Complementary Catalyst for the Suzuki-Miyaura Coupling in Water., By Sanjeeva Thunga, Soumya Poshala, Hari Prasad Kokatla, Elsevier, Tetrahedron Letters, vol.60, pp.2046, 2019
    A Facile One-Pot Synthesis of 2,2,2-Trichloroacetates Through Acid-Catalyzed Deimination and Its Applications., By Soumya Poshala, Sanjeeva Thunga, Sivaparwathi Golla, Vanaparthi Satheesh, Hari Prasad Kokatla, Wiley, Chemistry Select, vol.4, pp.10466, 2019
    Rongalite-promoted metal-free aerobic ipso-hydroxylation of arylboronic acids under sunlight: DFT mechanistic studies, By Sivaparwathi Golla, Soumya Poshala, Ravinder Pawar, Hari Prasad Kokatla, Elsevier, Tetrahedron Letters, vol.61, pp.151539, 2019
    Methyl 2-Nitrosobenzoate, A Simple Dehydrating Agent for the Synthesis of Nitriles from Aldoximes. , By Sanjeeva Thunga, Soumya Poshala, Hari Prasad Kokatla, Wiley, Chemistry Select, vol.3, pp.4425, 2018
    In Situ Generation of Copper Nanoparticles by Rongalite and Their Use as Catalyst for Click Chemistry in Water., By Soumya Poshala, Sanjeeva Thunga, Saikumar Manchala, Hari Prasad Kokatla, Wiley, Chemistry Select, vol.3, pp.13759, 2018
    Facile functionalization at the C4 position of pyrimidine nucleosides via amide group activation with (benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate (BOP) and biological evaluations of the products, By Hari K. Akula, Hariprasad Kokatla, Graciela Andrei, Robert Snoeck, Dominique Schols, Jan Balzarini, Lijia Yang and Mahesh K. Lakshman , RSC, Organic & Biomolecular Chemistry, vol.15, pp.1130-1139, 2017
    Structure-Based Design of Novel Human Toll-like Receptor 8 Agonists, By Dr. Hari Prasad Kokatla, Dr. Diptesh Sil, Dr. Hiromi Tanji, Dr. Umeharu Ohto, Subbalakshmi S. Malladi, Lauren M. Fox, Prof. Toshiyoki Shimizu, Prof. Sunil A. David, Wiley-VCH, ChemMedChem, vol.9, pp.719-723, 2014
    Exquisite Selectivity for Human Toll-Like Receptor 8 in Substituted Furo[2,3-c]quinolines, By Hari Prasad Kokatla, Diptesh Sil, Subbalakshmi S. Malladi, Rajalakshmi Balakrishna, Alec R. Hermanson†Lauren M. Fox, Xinkun Wang, Anshuman Dixit, Sunil A. David, ACS, Journal of Medicinal Chemistry, vol.56, pp.6871–6885, 2013
    Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo[4,5-c]quinolines, By Hari Prasad Kokatla,a Euna Yoo, Deepak B. Salunke, Diptesh Sil, Cameron F. Ng, Rajalakshmi Balakrishna, Subbalakshmi S. Malladi, Lauren M. Foxa and Sunil A. David, RSC, Organic & Biomolecular Chemistry, vol.11, pp.1179-1198, 2013
    Two-Step, One-Pot Synthesis of Inosine, Guanosine, and 2′-Deoxyguanosine O6-Ethers via Intermediate O6-(Benzotriazol-1-yl) Derivatives, By Hari Prasad Kokatla, Mahesh K. Lakshman, Wiley-VCH, Current Protocols in Nucleic Acid Chemistry, vol.49, pp.1.26. 1-1.26. 16, 2012
    Reduction of Amine N-Oxides by Diboron Reagents, By Hari Prasad KokatlaPaul F. ThomsonSuyeal Bae, Venkata Ramana Doddi and Mahesh K. Lakshman, ACS, The Journal of Organic Chemistry, vol.76, pp.7842–7848, 2011
    An improved method of ring closing metathesis in the presence of basic amines: application to the formal synthesis of (+)-lentiginosine and other piperidines and carbamino sugar analogs, By Rima Lahiri, Hari Prasad Kokatla, Yashwant D. Vankar, Elsevier, Tetrahedron Letters, vol.52, pp.781-786, 2011
    Synthesis of (−)-Deoxoprosophylline, (+)-2-epi-Deoxoprosopinine, and (2R,3R)- and (2R,3S)-3-Hydroxypipecolic Acids from d-Glycals, By Hari Prasad KokatlaRima LahiriPavan K. KancharlaVenkata Ramana DoddiYashwant D. Vankar, ACS, The Journal of Organic Chemistry, vol.75, pp. 4608–4611, 2010
    One-Pot Etherification of Purine Nucleosides and Pyrimidines, By Hari Prasad Kokatla and Mahesh K. Lakshman, ACS, Organic Letters, vol.12, pp.4478–4481, 2010
    A concise route to (−)-shikimic acid and (−)-5-epi-shikimic acid, and their enantiomers via Barbier reaction and ring-closing metathesis, By Pavan K. Kancharla, Venkata Ramana Doddi, Hariprasad Kokatla, Yashwant D. Vankar, Elsevier, Tetrahedron Letters, vol.50, pp.6951-6954, 2009
    Synthesis of Hybrids of D-Glucose and D-Galactose with Pyrrolidine-Based Iminosugars as Glycosidase Inhibitors, By Venkata Ramana Doddi, Hari Prasad Kokatla, A. P. John Pal, Ranjan K. Basak, Yashwant D. Vankar, Wiley-VCH, European Journal of Organic Chemistry, vol.2008, pp.5731-5739, 2008
    Stereoselective synthesis of safingol and its natural stereoisomer from d-glycals, By Hari Prasad Kokatla, Ram Sagar, Yashwant D. Vankar, Elsevier, Tetrahedron Letters, vol.49, pp.4728-4730, 2008
    Conference(s)
    N-Oxide Induced Ugi Reaction: A Novel Synthesis of Quinoline-C2_Amino Amides/Spiro via Deoxygenative C(sp2)-H Functionalization By Kokatla Hari Prasad, Naveen kumar Anugu, 32 CRSI National Symposium in Chemistry (CRSI-NSC-32), Feb 02-04 , 2024, 2023
    A Facile Synthesis of 2-(1-Metyl-1H-Indol-3-yl) quinoline via Metal free C-H Functionalization By Neetika Singh, Hari Prasad Kokatla, International Conference on Organic & Medicinal Chemistry from 28th- 30th June,2023, 2023
    Solvent Assisted Reductive Dechlorination of 3,3-Dichlorooxindoles by Rongalite: Rapid Access to 3-Chloro-2-Oxindoles and 2- Oxindoles By Jalagam Swathi, Hari Prasad Kokatla, Recent Advances in Inorganic and Organometallic Chemistry RAdIOC-2023, 2023
    Book Chapter(s)
    Syntheses of Human TLR8-Specific Small-Molecule Agonists By Mallesh Beesu, Hari Prasad Kokatla & Sunil A. David in Vaccine Adjuvants, Springer, eBook, 2017
    Patent(s)
    Exquisite Human Toll-like Receptor 8-Selective Agonistic Activities of Substituted Furo[2,3-c]quinolines (WO 2015/095780/ A1)
    PROJECT / CONSULTANCY
    Transition Metal-Free C(sp2)–H methylenation of Heterocycles by Rongalite: A rapid access to C1-Homologation
    Role: Principal Investigator
    Type: Research
    Sponsor: SERB-EEQ
    Project Cost (INR): 4330000
    Date of Commencement: 03-02-2023   Date of Completion: 02-02-2026
    Duration: 36 Months
    Status: Completed
    Rongalite-induced Consecutive C1-Homologation/Fluorination Strategy for selective fluorination of Organic molecules
    Role: Principal Investigator
    Type: Research
    Sponsor: SERB-SCP
    Project Cost (INR): 4125264
    Date of Commencement: 02-11-2022   Date of Completion: 01-11-2025
    Duration: 36 Months
    Status: Completed
    Rongalite/Molecular Oxygen: A mild and green reagent for oxidation of organic substrates under sunlight
    Role: Principal Investigator
    Type: Research
    Sponsor: SERB-EEQ
    Project Cost (INR): 4102000
    Date of Commencement: 20-03-2019   Date of Completion: 19-03-2022
    Duration: 36 Months
    Status: Completed
    Novel glycosylation methods and their application to biologically important molecules
    Role: Principal Investigator
    Type: Research
    Sponsor: DST-INSPIRE
    Project Cost (INR): 3500000
    Date of Commencement: 30-01-2015   Date of Completion: 29-01-2020
    Duration: 60 Months
    Status: Completed
    N-Heterocyclic Carbene Catalyzed Tandem [2+2] and [4+2] Cycloaddition Reactions): Application in the Synthesis of Bioactive Compounds
    Role: Principal Investigator
    Type: Research
    Sponsor: SERB-FAST TRACK
    Project Cost (INR): 2300000
    Date of Commencement: 09-02-2016   Date of Completion: 08-02-2019
    Duration: 36 Months
    Status: Completed
    RESEARCH FELLOWS / PhD STUDENTS
    Current PhD Students
    Chinthakunta Nagaraju
    Area of Research: C-2 activation of Quinoline N-oxides
    DANISH MANZOOR AHMAD
    Area of Research: Metal-Free C-H (sp2) functionalization
    Inapanuri Madhu
    Area of Research: Functionalization of N-Heterocycles by Rongalite
    KandukuriRambabu
    Area of Research: Metal-Free C-H(sp2) Methylenation by Rongalite
    MADALA NARESH
    Area of Research: Metal-Free C-H (sp2) functionalization
    MEDABOINA SRINIVAS
    Area of Research: Development of New Synthetic Methodologies for the Preparation of Bioactive Heterocyclic Molecules
    Naddi Nagaraju
    Area of Research: Selective Flourination of Organic Molecules
    Neetika Singh
    Area of Research: Metal-Free C-H(sp2) Functionalization of Heterocycles
    N. Suresh Babu
    Area of Research: NOVEL SYNTHESIS AND CHARACTERISATION OF ACTIVE PHARMACEUTICAL INGREDIENTS
    Raju Mamidi
    Area of Research: Development of Green Methodologies by using Rongalite
    Ramesh Konakalla
    Area of Research: Synthesis of biologically active galloyl pyrrolidine derivatives
    Swathi Jalagam
    Area of Research: Rongalite Induced Organic Synthesis.
    Previous PhD Students
    Soumya Poshala (2022)
    Area of Research: Development of New Methodologies for C-C, C-N and C-O Bond F
    Naveenkumar Anugu (2022)
    Area of Research: C(sp2)-H Functionalization of Quinolines, Imidazo[1,2-a]Pyri
    Golla Sivaparwathi (2022)
    Area of Research: APPLICATIONS OF RONGALITE, THIOUREA DIOXIDE AND SODIUM DITH
    Sanjeeva Thunga (2020)
    Area of Research: DEVELOPMENT OF NEW METHODOLOGIES IN ORGANIC SYNTHESIS USING
    CONFERENCE / WORKSHOP / SYMPOSIUM / SHORT TERM COURSE / FACULTY DEVELOPMENT PROGRAMME
    AWARDS AND ACCOLADES
    2020
    Young Researcher Award (Sciences)- 2020
    2019
    Associate Fellow
    2011
    CUNY Travel Grant Award From RF-CUNY
    ADDITIONAL RESPONSIBILITIES
    •  Director’s Nominee for Ph.D Selections (December, 2023 - December, 2023)
    •  Associate Dean, Faculty Welfare (July, 2023 - June, 2025)
    •  Associate Dean, Faculty Welfare (July, 2023 - June, 2025)
    •  Director’s Nominee for Ph.D Selections (June, 2023 - June, 2023)
    •  Academic & Research Group: (Continuing from June, 2023)
    •  Coordinator: 5 Years Int M.Sc. 5 th Year (Continuing from June, 2023)
    •  Departmental Academic Appeal Committee (Continuing from June, 2023)
    •  Departmental Academic Review Committee (Continuing from June, 2023)
    •  PIC-Research Students (Progress & Graduation) (Continuing from June, 2023)
    •  Committee member for 20th Convocation of the Institute (September, 2022 - September, 2022)
    •  Faculty I/c Youth Red Cross (Continuing from August, 2021)
    •  Faculty I/c - Institute (Continuing from August, 2019)
    •  Faculty I/c for 400 MHz NMR (Continuing from January, 2019)
    •  I. B.Tech Lab Course Coordinator (July, 2018 - July, 2021)
    •  Faculty advisor (Students Elections) (Continuing from August, 2015)
    •  Faculty representative, Training & placement (July, 2015 - June, 2016)
    •  Member, DAC PG&R (June, 2015 - June, 2016)
    •  Initiator, Rate Contract (Chemicals and Glassware) (January, 2015 - January, 2016)
    •  Faculty Coordinator II MSc (Org Chem) (July, 2014 - June, 2015)
    •  Faculty-in-Charge, Chemistry Association (July, 2014 - July, 2019)
    •  Faculty-in-Charge, FT-IR Instrument (July, 2014 - July, 2018)
    •  Monitor & Mentor for the I-B.Tech. Students (July, 2014 - July, 2018)
    •  Seminars for M.Sc. III Semester (Organic) (July, 2014 - July, 2018)
     Last updated on January 17, 2026