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Prof. Prakash Saudagar

Associate Professor

Department of Biotechnology

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Information

Room No: 414 +91-870-2462898 ps@nitw.ac.in Bio Sketch

    Key Notes

    • Journal(s): 55
    • Conference(s): 36
    • Book Chapter(s): 25
    • Text Book(s): 3
    • PhD: Current - 4  Awarded - 3
    • PDF: Guided - 1
    • Event(s) Organized: Conference - 1  Workshop - 2  Short Term Course - 1  FDP - 1

    119

    PUBLICATIONS

    7

    DOCTORAL STUDENTS

    6

    PROJECTS

    2

    PATENTS

    Research Areas

    Cancer & Infectious Disease Drug Targets,
    Molecular Cell Biology & Protein Biochemistry
    EDUCATION QUALIFICATION
    Degree Institute Year
    Doctor of Philosophy IIT Guwahati 2013
    Master of Technology OUCT (Osmania University) 2009
    Bachelor of Technology CMRCET (JNTU Hyderabad) 2007
    COURSES HANDLED
    Course L-T-P Credit Degree Level
    Biology for Engineers(BT1161) 2-0-0 2 UG
    Molecular and Cellular Biology(BT16003) 3-0-2 4 PG
    Cell Biology(BT1206) 3-0-0 3 UG
    Cell Biology(BT253) 3-0-0 3 UG
    Molecular and Cellular Biology(BT5102) 3-0-0 3 PG
    RESEARCH IDs
    ORCID
    ORC ID
    ISI Researcher ID
    ISI Researcher ID
    Scopus
    SCOPUS ID
    Google Scholar
    Google Scholar ID
    PUBLICATIONS
    Journal(s)
    In-vitro biomineralization study of eco-friendly synthesized borosilicate glass with strontium oxide as dopant, By Satish Jain; Md Monirujjaman; Locherla Daloji; Raghavendra Gujjala; P Abdul Azeem; Raj Kumar Samudrala; Prakash Saudagar; Shakuntala Ojha, Elsevier , Ceramics International, vol.Volume 51 Issue13, pp.18265-18275, 2025
    The landscape of intrinsically disordered proteins in Leishmania parasite: Implications for drug discovery, By Seshaveena Gollapalli, Banesh Sooram, Hitesh Sugandh, Prakash Saudagar, Elesevier, International Journal of Biological macromolecules, vol.283, pp.137290, 2024
    A novel approach to design chimeric multi epitope vaccine against Leishmania exploiting infected host cell proteome, By Sooram Banesh, Neharika Gupta, Chethireddy Vihadhar Reddy, Uppuladinne Mallikarjunachari, Nupoor Patil, Sonavane Uddhavesh, Prakash Saudagar*, Cell Press , Heliyon, vol.10, pp., 2024
    Design and evaluation of a multiepitope vaccine for pancreatic cancer using immune-dominant epitopes derived from the signature proteome in expression datasets, By S Banesh, N Patil, VR Chethireddy, A Bhukmaria, Prakash Saudagar*, Springer Nature , Medical Oncology, vol.41 (5), pp.90, 2024
    A comprehensive study on bioactivity, mechanical and tribological behavior of copper-doped borosilicate glass derived from natural waste for dental applications, By Satish Jain, Raghavendra Gujjala, Hemanth Boyina, P Abdul Azeem, Raj Kumar Samudrala, Prakash Saudagar, Sooram Banesh. , Elsevier , Ceramics International, vol.50 (16), pp.28988-29000, 2024
    Pharmacophore-guided drug design using LdNMT as a model drug target for leishmaniasis, By B Sooram, U Mallikarjunachari, S Uddavesh, Prakash Saudagar*, Taylor & Francis , Journal of Biomolecular Structure and Dynamics, vol.42 (2), pp.863-875, 2024
    An anti-leishmanial compound 4′,7-dihydroxyflavone elicits ROS-mediated apoptosis-like death in Leishmania parasite., By Sasidharan S. and; Prakash Saudagar*, FEBS Press, The FEBS Journal, vol.Volume 290, Issue 14, pp.3646-3, 2023
    4’,7-dihydroxyflavone conjugated carbon nanotube formulation demonstrates improved efficacy against Leishmania parasite, By Sasidharan S. and; Prakash Saudagar*, Elsevier, BBA - General Subjects, vol.Volume 1867, Issue 10, pp.130416, 2023
    Molecular dynamics of the ERRγ ligand-binding domain bound with agonist and inverse agonist., By S Sasidharan, K Radhakrishnan, JY Lee, Prakash Saudagar, V Gosu, D Shin, Public Library of Science, Plos one, vol.18(4): e0283364, pp.18, 2023
    Deciphering the intrinsic dynamics of unphosphorylated IRAK4 kinase bound to type I and type II inhibitors., By V Gosu, S Sasidharan, Prakash Saudagar, K Radhakrishnan, HK Lee, D Shin, Elsevier, Computers in Biology and Medicine, vol.160, pp.106978, 2023
    meso-Carbazole decorated BODIPYs–an electron donor–acceptor system with excellent fluorosolvato/vapochromic behavior, aggregation-induced emission, and antileishmanial activity, By D Mathew, S Sasidharan, Prakash Saudagar, S Sujatha, P Parameswaran , RSC , New Journal of Chemistry , vol.47 (17), pp.8277-8290, 2023
    Gold and silver nanoparticles functionalized with 4’,7-dihydroxyflavone exhibit activity against Leishmania donovani., By Sasidharan S. and; Prakash Saudagar*, Elsevier, Acta Tropica, vol.231, pp.106448, 2022
    Recent Advances and Reports on Encapsulation in the Food Matrix: A Review, By Shital B Potdar, Prakash Saudagar, Irina Potoroko, Uday Bagale, Shriram Sonawane, Shirish H Sonawane, Bentham science , Current Pharmaceutical Biotechnology, vol., pp., 2022
    Discovery of compounds inhibiting SARS-COV-2 multi-targets, By Santanu Sasidharan, Neellohit Sarkar, and Prakash Saudagar*, Taylor & Francis , Journal of Biomolecular Structure and Dynamics , vol.41(6), pp.1-16, 2022
    Knockout of Tyrosine Aminotransferase Gene by Homologous Recombination Arrests Growth and Disrupts Redox Homeostasis in Leishmania Parasite, By Sasidharan S. and; Prakash Saudagar*, Springer Nature , Parasitology Research, vol.121(11), pp.3229-3241, 2022
    Amyloid Cross-Seeding: Mechanism, Implication, and Inhibition., By Subedi, Sushma#, Santanu Sasidharan#, Niharika Nag, Prakash Saudagar*, and Timir Tripathi. , MDPI , Molecules, vol.27, pp.1776, 2022
    Phase separation of FG-nucleoporins in nuclear pore complexes, By Nag, Niharika#, Santanu Sasidharan#, Vladimir N. Uversky, Prakash Saudagar*, and Timir Tripathi*, Elsevier , Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, vol.Volume 1869, Issue 4,, pp.119205, 2022
    Photodynamic Evaluation of Triazine Appended Porphyrins as Anti-Leishmanial and Anti-tumor Agents, By Manathanath, Monisha, Santanu Sasidharan, Prakash Saudagar, Unnikrishnan Gopalakrishna Panicker, and Subramaniam Sujatha, Elsevier , Polyhedron, vol.217, pp.115711, 2022
    Influence of SeO2 on in vitro bioactivity and antibacterial activity of CaF2–CaO–B2O3–P2O5–SrO glass system, By Madhavi, B., A. Siva Sesha Reddy, P. Syam Prasad, Prakash Saudagar, P. Venkateswara Rao, V. Ravi Kumar, and N. Veeraiah, Elsevier , Materials Chemistry and Physics , vol.278, pp.125653, 2022
    Biofunctionalized Chrysin-conjugated gold nanoparticles neutralize Leishmania parasites with high efficacy., By Raj S.;Sasidharan S.;Tripathi T.; and Prakash Saudagar*, Elsevier, International Journal of Biological Macromolecules, vol.205, pp.211-19, 2022
    ANN‐based modelling of peppermint flavour encapsulation process with ultrasound approach., By Potdar, Shital B., Bharat A. Bhanvase, Prakash Saudagar, Irina Potoroko, and Shirish H. Sonawane. , Wiley, The Canadian Journal of Chemical Engineering , vol.100(8), pp.1718-1728, 2021
    Critical Insight into Plausible Acquired Tocopherol Pathway in Neglected Human Trypanosomatids, By Santanu Sasidharan, Timir Tripathi, and Prakash Saudagar*, ACS, ACS omega , vol.6 (47), pp.31396-31403, 2021
    Computational Insights into the Structural Dynamics of MDA5 Variants Associated with Aicardi– Goutières Syndrome and Singleton–Merten Syndrome, By Gosu, Vijayakumar, Santanu Sasidharan, Prakash Saudagar, Hak-Kyo Lee, and Donghyun Shin. , MDPI , Biomolecules, vol.11 (8), pp.1251, 2021
    Interface‐based design of the favipiravir‐binding site in SARS‐CoV‐2 RNA‐dependent RNA polymerase reveals mutations conferring resistance to chain termination, By Padhi, Aditya K., Jagneshwar Dandapat, Prakash Saudagar, Vladimir N. Uversky, and Timir Tripathi., Wiley, FEBS letters , vol.595 (18), pp.2366-2382, 2021
    Leishmaniasis: where are we and where are we heading?, By Sasidharan S, and Prakash Saudagar *, Springer Nature , Parasitology Research, vol.120(5), pp.1541-1554, 2021
    Therapeutic p28 peptide targets essential H1N1 influenza virus proteins: insights from docking and molecular dynamics simulations., By Santanu Sasidharan, Vijayakumar Gosu, Donghyun Shin, Subhradip Nath, Timir Tripathi, and Prakash Saudagar*, Springer Nature , Molecular Diversity , vol.1, pp.15, 2021
    Synthesis, TDDFT Calculations and Biological Evaluation of Dicationic Porphyrins as Groove Binders and Antimicrobial Agents, By Mathew, Diana, Jagadeesan Ramesh, Santanu Sasidharan, Kannan Subburaj, Prakash Saudagar, Pattiyil Parameswaran, and Subramaniam Sujatha, Wiley , ChemistrySelect, vol.6(3), pp.396-409, 2021
    High-throughput rational design of the remdesivir binding site in the RdRp of SARS-CoV-2: implications for potential resistance., By Padhi, Aditya K., Rohit Shukla, Prakash Saudagar*, and Timir Tripathi*. , Cell Press , iScience , vol.24 (1), pp.101992, 2021
    Flavones reversibly inhibit L. donovani tyrosine aminotransferase by binding to the catalytic pocket: An integrated in silico-in vitro approach., By Santanu Sasidharan and Prakash Saudagar*. , Elsevier, International Journal of Biological Macromolecules , vol.164, pp.2987-3004, 2020
    Mapping N-and C-terminals of L. donovani tyrosine aminotransferase by gene truncation strategy: a functional study using in vitro and in silico approaches., By Santanu Sasidharan and Prakash Saudagar*. , Nature , Scientific reports , vol.10 (1), pp.1-15, 2020
    Bacterial protein azurin and derived peptides as potential anti-SARS-CoV-2 agents: Insights from molecular docking and molecular dynamics simulations., By Santanu Sasidharan, Chandrabose Selvaraj, Sanjeev Kumar Singh, Vikash Kumar Dubey, Sachin Kumar, Arsenio M. Fialho, and Prakash Saudagar*, Taylor & Francis , Journal of Biomolecular Structure and Dynamics , vol.39(15), pp.5706-5721, 2020
    Computational design of a potential multi-epitope subunit vaccine using immunoinformatics to fight Ebola virus., By Kadam, Ajinkya, Santanu Sasidharan# and Prakash Saudagar*, Elsevier , Infection, Genetics and Evolution , vol.85, pp.104464, 2020
    Review on natural products as an alternative to contemporary anti-leishmanial therapeutics., By Raj, Shweta, Santanu Sasidharan, S. N. Balaji, Vikash Kumar Dubey, and Prakash Saudagar*, Springer Nature , Journal of Proteins and Proteomics , vol.11, pp.135-158, 2020
    An overview of biochemically characterized drug targets in metabolic pathways of Leishmania parasite., By Raj, Shweta, Santanu Sasidharan, S. N. Balaji, and Prakash Saudagar*, Springer Nature , Parasitology Research, vol.119, pp.2025-2037, 2020
    Concerted motion of structure and active site charge is required for TAT activity in Leishmania parasite., By Santanu Sasidharan and Prakash Saudagar*, Elsevier , Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, vol.232, pp.118133, 2020
    Utilising capsid proteins of poliovirus to design a multi-epitope-based subunit vaccine by immunoinformatics approach, By Bohra, Nitin#, Santanu Sasidharan#, Shweta Raj, S. N. Balaji, and Prakash Saudagar*, Taylor & Francis , Molecular Simulation , vol.46.5, pp.419-428, 2020
    Exploring the Zika Genome to Design a Potential Multiepitope Vaccine Using an Immunoinformatics Approach., By Mittal, Ayushi#, Santanu Sasidharan#, Shweta Raj, S. N. Balaji, and Prakash Saudagar*, Springer Nature , International Journal of Peptide Research and Therapeutics, vol.26(4), pp.2231-2240, 2020
    Green-Synthesized FeSO4 Nanoparticles Exhibit Antibacterial and Cytotoxic Activity by DNA Degradation., By Bharath, B.#, Santanu Sasidharan#, S. K. Bhamidipati, and Prakash Saudagar*, Bentham science , Current pharmaceutical biotechnology , vol.21.7, pp.587-595, 2019
    Biochemical characterization and chemical validation of Leishmania MAP Kinase-3 as a potential drug target. , By Raj, S., G. Saha, Santanu Sasidharan, V.K. Dubey, and Prakash Saudagar*, Nature, Scientific Reports, vol.9(1), pp.16209, 2019
    Biochemical and structural characterization of tyrosine aminotransferase suggests broad substrate specificity and a two‐state folding mechanism in L. donovani., By Santanu Sasidharan and Prakash Saudagar*, Wiley , FEBS open bio , vol.9(10), pp.1769-1783, 2019
    Identification of lead molecules against potential drug target protein MAPK4 from L. donovani: An in-silico approach using docking, molecular dynamics and binding free energy calculation, By Raj, Shweta#, Santanu Sasidharan#, Vikash Kumar Dubey, and Prakash Saudagar*, PLOS , PLOS One , vol.14(8), pp.221331, 2019
    Episomal expression of human glutathione reductase (HuGR) in Leishmania sheds light on evolutionary pressure for unique redox metabolism pathway: Impaired stress tolerance ability of Leishmania donovani, By Prakash, Jay, Sunita Yadav, Gundappa Saha, Adarsh Kumar Chiranjivi, Suresh Kumar, Santanu Sasidharan, Prakash Saudagar*, and Vikash Kumar Dubey*, Elsevier , International journal of biological macromolecules, vol.121, pp.498-507, 2019
    Novel Schiff base metal complexes: synthesis, characterization, DNA binding, DNA cleavage and molecular docking studies, By Bheemarasetti, Mayuri, Kavitha Palakuri, Shweta Raj, Prakash Saudagar, Durgaiah Gandamalla, Narsimha Reddy Yellu, and Laxma Reddy Kotha, Springer Nature , Journal of the Iranian Chemical Society, vol.15(6), pp.1377-1389, 2018
    Molecular Mechanisms of In vitro Betulin Induced Apoptosis of Leishmania donovani., By Prakash Saudagar and Vikash K. Dubey, ASTMH, USA , American Journal of Tropical Medicine and Hygiene, vol.90, pp.354-360, 2014
    Carbon Nanotube Based Betulin Formulation shows better efficacy against Leishmania parasite, By Prakash S and Vikash K. Dubey, Elsevier, Parasitology International, vol.63, pp.772-776, 2014
    In vivo assessment of antileishmanial property of 4-(4,4,8-Trimethyl-7-oxo-3- oxabicyclo[3.3.1]non-2-yl)- benzoic acid methyl ester, an oxabicyclo [3.3.1] nonanones, By Prakash Saudagar, Shyam Lal Mudavath, Pipas Saha, Anil K. Saikia, Shyam Sundar and Vikash Kumar Dubey, Bentham science, Letters in Drug Design and Discovery, vol.11, pp.937-939, 2014
    Discovery of novel anti- leishmanial agents targeting LdLip3 lipase, By Saravanan P, Prakash Saudagar, Vikash K. Dubey and Sanjukta Patra, Elsevier , Journal of Molecular Graphics and Modelling, vol.49, pp.68-79, 2014
    Molecular mechanism underlying antileishmanial effect of oxabicyclo[3.3.1]nonanones: Inhibition of key redox enzymes of the pathogen, By Prakash Saudagar, Saha P, Anil K. Saikia and Vikash K. Dubey, Elsevier, European Journal of Pharmaceutics and Biopharmaceutics, vol.85, pp.569-577, 2013
    Miltefosine unresponsive Leishmania donovani has better ability of resist reactive oxygen species, By Prakash Saudagar, Mousumi Das, Shyam Sunder and Vikash K. Dubey, Wiley, FEBS Journal, vol.280, pp.4807-4815, 2013
    Evaluation of a diospyrin derivative as antileishmanial agent and potential modulators of ornithine decarboxylase of Leishmania donovani., By Hazara S, Ghosh S, Sharma MD, Das M, Prakash S, Prajapati V.K, Dubey V.K, Sundar S, Hazra B, Elsevier, Experimental Parasitology, vol.135, pp.407-413, 2013
    Epitopic analysis of potential vaccine candidate in Leishmania infantum for development of human vaccine., By Abhinav Grover, Sushil K. Shakyawar, Prakash Saudagar, Vikash K. Dubey and Sundar Durai. , Bentham science , Letters in Drug Design & Discovery, vol.9, pp.698-705, 2012
    Nanobiosciences: A contemporary line for Antiparasitic Drug, By Ruchika Bhardwaj, Prakash Saudagar and Vikash K. Dubey., LumiText , Molecular and Cellular Pharmacology, vol.4, pp.97-103, 2012
    Cloning, expression, characterization, and inhibition studies on trypanothione synthetase, a drug target enzyme, from Leishmania donovani, By Prakash Saudagar and Vikash K. Dubey, De Gruyter , Biological Chemistry, vol.392, pp.1113-1122, 2011
    Screening natural products database for identification of potential anti-leishmanial chemotherapeutic agents. , By Santhosh K. Venkatesan, Prakash Saudagar, Anil K. Shukla and Vikash K. Dubey, Springer Nature , Interdiscip. Sci. Comput. Life Sci. , vol.3, pp.217-231, 2011
    Identification of novel inhibitors of trypanothione synthetase from two Leishmania species: Comparative in silico analysis., By Santhosh K. Venkatesan, Prakash Saudagar and Vikash K. Dubey, Springer Nature, Journal of Proteins and Proteomics, vol.2, pp.41-48, 2011
    Conference(s)
    Deciphering Essential Proteins in Leishmania: Structural and Functional Approaches Toward New Therapeutic Targets By Prakash Saudagar, National Conference on “Innovations in Computational Drug Discovery (ICDD–2026), 2026
    Unveiling Intrinsically Disordered Proteins in Leishmania Parasite A New Frontiers in Drug Targeting By Gollapalli Seshaveena, Dr. Prakash Saudagar, Global Scientific Conference 2025, 2025
    Decoding Intrinsically Disorder proteins in Leishmania: AGateway to Novel Drug Targets By Gollapalli Seshaveena, Dr. Prakash Saudagar, International e-Conference on Multifaceted Applications in Biotecnology and Applied Sciences (e-COMBAS 2.0) , 2025
    Exploring the Therapeutic potential of azurin as an anti-leishmanial agent. By Vihadhar Reddy Ch, Dr Prakash Saudagar, Drug Discovery and Translational Healthcare 2025. (DDTH 2025), 2025
    A Dual- Targeting Multi-Epitope Vaccine Candidate Against Leishmaniasis: Harnessing Host-Pathogen Interface Through Computational Vaccinology. By Vihadhar Reddy Ch, Dr Prakash Saudagar, Global Scientific Conference 2025, 2025
    A Synergistic Targeting Multi-Epitope Vaccine Candidate Against Leishmaniasis: Employing Host-Pathogen Interface Through immunoinformatic Computational approach. By Vihadhar Reddy Ch, Dr Prakash Saudagar, International e-Conference on Multifaceted Applications in Biotecnology and Applied Sciences (e-COMBAS 2.0) , 2025
    Exploring Drug Target Proteins in Leishmania Parasite By Prakash Saudagar, One Week Interdisciplinary Short-Term Programme Bioinformatics and Biological Research, 2025
    Thiol-Redox Regulation in Leishmania: Insights into Parasite Survival and Therapeutic Opportunities By Prakash Saudagar, Emerging Strategies and Innovations for Combating Diseases in Animals and Plants” (ESCAP-2025), 2025
    Unveiling Therapeutic Targets in Leishmania: Insights into Redox metabolism By Prakash Saudagar, Global Summit on Innovative Drug Design, Discovery, and Translational Research, 2025
    Thiol-Redox Homeostasis in Leishmania: Mechanistic Insights and Therapeutic Prospects By Prakash Saudagar, Asian Neglected Tropical Diseases Conference-2025 (NTD ASIA-2025), 2025
    Characterization of Key Proteins in Leishmania: Exploring Novel Drug Targets for Anti-leishmanial Therapy By Prakash Saudagar, Drug Discovery and Translational Healthcare 2025, 2025
    Two Days (02) National Workshop on Viksit Bharat 2047 – Atmanirbhar North East By Prakash Saudagar, ., 2024
    Biotechnology and Indian Knowledge system By Prakash Saudagar, Nalanda Gyan Kumbh" National Academic Conclave, 2024
    Investigating Leishmania Tyrosine Aminotransferase (LdTAT) as a Promising Drug Target By Prakash Saudagar, Conference on Structural Biology and Drug Discovery (CSBDD) Commemoration of the 102nd Birthday of Prof. G. N. Ramachandran, FRS, 2024
    Cancer & Infectious Disease Drug Targets By Prakash Saudagar, International e-Conference on Multifaceted Applications in Biotechnology and Applied Sciences (e-COMBAS 1.0), 2024
    Microbial Metagenomics and Next Generation Sequencing By Prakash Saudagar, AICTE-sponsored ATAL-FDP , 2024
    National Bioengineering Conference – 2023 (NBC-2023) By Prakash Saudagar, National Bioengineering Conference – 2023 (NBC-2023), 2023
    Exploring the drug target proteins in Leishmania Parasite By Prakash Saudagar, Advances and Innovations in Biotechnology-2023 – Hybrid mode”, organized by the Centre for Bio Separation Technology, 2023
    Exploring Enzymes of Trypanothione metabolism in Leishmania Parasite as Promising Drug Targets By Prakash Saudagar, International Conference on Structural Biology and Drug Discovery (ICSBDD-2023), 2023
    Exploring Drug Target Proteins in Leishmania Parasite By Prakash Saudagar, Conference on Structural Biology and Drug Discovery (CSBD), 2023
    Studies on Leishmania donovani tyrosine aminotransferase as potential drug target By Prakash Saudagar, National Conference on Computational and Biochemical Drug Discovery [NCCBDD-2021], 2021
    Biochemical and inhibition studies on Leishmania donovani tyrosine aminotransferase. By Santanu Sasidharan* and Prakash Saudagar, Parasites Online conference conducted by British Society for Parasitology, 2021
    Studies on Leishmania MAP Kinase for the development of novel anti-parasitic strategies. Shweta Raj and Prakash Saudagar By Shweta, Dr Prakash Saudagar, Recent Advancements in Biochemical Engineering and Biotechnology [RABEB-2019], 2019
    Studies on tyrosine aminotransferase from Leishmania donovani : a potential drug target. By Santanu Sasidharan , Dr Prakash Saudagar, National conference in Molecular biotechnology, 2019
    Biochemical and in-silico characterization of Tyrosine aminotransferase from Leishmania donovani: a potential drug target By Santanu Sasidharan* and Prakash Saudagar, RABEB-2019, 2019
    Studies on mitogen activated protein kinase of Leishmania parasite as a therapeutic target By Prakash Saudagar, Recent Advancements in Biochemical Engineering & Biotechnology (RABAB), 2019
    Molecular mechanism and increased antileishmanial activity of carbon nanotube based betulin forulation By Prakash Saudagar and Vikash Kumar Dubey, International Conference on Nanomedicine and Nanobiotechnology-2016 (ICONAN-2016), 2016
    Redox Metabolism in Leishmania Parasite By Prakash Saudagar, National Conference on Recent Developments in Medical Biotechnology and Structure Based Drug Designing-2015 (RDMBSBDD-2015), 2015
    7th IEEE International Conference on Technology For Education-2015 (T4E-2015) By Prakash Saudagar*, 7th IEEE International Conference on Technology For Education-2015 (T4E-2015), 2015
    Betulin attached to functionalized carbon nanotubes showed better efficacy against Leishmania parasite By Prakash Saudagar* and Vikash Kumar Dubey, 2nd International Conference on Infectious Diseases and Nanomedicine-2015 (ICIDN-2015), 2015
    Computational Drug Design using Molecular Docking and Virtual Screening By Prakash Saudagar*, Short Term Training Programme , 2015
    Oxabicyclo derivatives as a new class of antileishmanial agents:target identification and understanding molecular mechanism of parasite death By Prakash Saudagar* and Vikash K. Dubey, International Meeting on Emerging Diseases and Surveillance (IMED 2013), 2013
    Trypanothion synthetase: A validated drug target enzyme from Leishmania donovani. By Prakash Saudagar and Vikash Kumar Dubey, The 18th International Conference (POST ISCBC-2012), 2012
    Current trends in anti- leishmanial drug discovery. By Vikash Kumar Dubey*, Anil Kuamr Shukla and Prakash Saudagar, International conference on New Horizones in Biotechnology, 2011
    Trypanothione Synthetase from L. donovani: Cloning, expression, characterization, and inhibition studies By Prakash Saudagar and Vikash Kumar Dubey*, 80th Annual Meeting of Society of Biological Chemists, 2011
    Molecular modeling, virtual screening and comparative analysis of. Trypanothione Synthetase from L. donovani and L. major for the identification of new inhibitors as a drug By Prakash Saudagar*, Santhosh Kannan Venkatesan and Vikash Kumar Dubey, International Conference on Frontiers on Biological Sciences, 2010
    Text Book(s)
    Protein Folding Dynamics and Stability: Experimental and Computational Methods. By Saudagar, P., and Tripathi, T (Published by: Springer, Singapore. [ISBN: 978-981-99-2078-5].), Reference Book, 2023
    Advanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics. By Saudagar, P., and Tripathi, T (Published by: Academic Press, USA. [ISBN: 978-032-39-9127-8]), Reference Book, 2023
    3. Recent Trends in Nanobiotechnology: Food and Biomedical Applications By K Divakar and Prakash Saudagar (Published by: Central West Publishing, Australia), Reference Book, 2019
    Book Chapter(s)
    Design of SaCas9-HF for Vivo Gene Therapy By K Tiwari, R Kumar, P Saudagar* in Gene, Drug, and Tissue Engineering,, Humana Press New York, USA., Reference Book, 2023
    Applications of Differential Scanning Calorimetry in Studying Folding and Stability of Proteins. By Sooram, B., Gupta, N., Chethireddy, V.R., Tripathi, T., P Saudagar*. in Protein Folding Dynamics and Stability., Springer, Singapore, Reference Book, 2023
    Molecular Dynamics Simulation to Study Protein Conformation and Ligand Interaction. By Sasidharan, S., Gosu, V., Tripathi, T., P Saudagar*. in Protein Folding Dynamics and Stability., Springer, Singapore, Reference Book, 2023
    pH-Based Molecular Dynamics Simulation for Analysing Protein Structure and Folding. By Sasidharan, S., Shukla, R., Tripathi, T., P Saudagar*. in Protein Folding Dynamics and Stability., Springer, Singapore, Reference Book, 2023
    Fluorescence Spectroscopy-Based Methods to Study Protein Folding Dynamics. By Kumar, R., Tripathi, T., P Saudagar*. in Protein Folding Dynamics and Stability., Springer, Singapore, Reference Book, 2023
    Interactions and interplay of MLOs with classical membrane-bound organelles By Sasidharan, Santanu, Niharika Nag, Timir Tripathi, and P Saudagar*. in Droplets of Life, Academic Press, USA., Reference Book, 2023
    Simplified CRISPR-Mediated DNA Editing in Multicellular Eukaryotes By R Kumar, K Tiwari, P Saudagar*; in Gene, Drug, and Tissue Engineering,, Humana Press New York, USA., Reference Book, 2023
    In Vitro Assay for the Assessment of Oxygen Depletion Triggers in Human Cell Lines, Associated with Improving Responses to Cancer Therapy.  By K Tiwari, R Kumar, G Saha, P Saudagar*; in Gene, Drug, and Tissue Engineering,, Humana Press New York, USA., Reference Book, 2023
    Gene Alterations Induced by Glutamine (Q) Encoding CAG Repeats Associated with Neurodegeneration. By G Saha, S Ghosh, VK Dubey, P Saudagar* in Gene, Drug, and Tissue Engineering,, Humana Press New York, USA., Reference Book, 2023
    Interactions and interplay of membrane-less organelles with classical membrane-bound organelles. By Sasidharan, S., Nag, N., Tripathi, T., and P Saudagar*. in Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid-Liquid Phase Separation., Academic Press, Reference Book, 2022
    Experimental methods to study the thermodynamics of protein–protein interactions. By Santanu Sasidharan, Niharika Nag, Timir Tripathi, and Prakash Saudagar*. in Advances in Protein Molecular and Structural Biology Methods,, Academic Press, Reference Book, 2022
    Prediction, validation, and analysis of protein structures: A beginner’s guide. By Santanu Sasidharan and Prakash Saudagar*. in Advances in Protein Molecular and Structural Biology Methods, Academic Press, Reference Book, 2022
    Fundamentals of spectroscopy for biomolecular structure and dynamics. By Nag, N., Sasidharan, S., and Saudagar, P., Tripathi, T.* in Advanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics., Academic Press, USA., Reference Book, 2022
    Applications of infrared spectroscopy to study proteins. By Sahu, R., Sooram, B., Sasidharan, S., Nag, N., Tripathi, T., and P Saudagar*. in Advanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics., Academic Press, USA., Reference Book, 2022
    Integration of spectroscopic and computational data to analyze protein structure, function, folding, and dynamics. By Prince, K., Sasidharan, S., Nag, N., Tripathi, T., and P Saudagar*. in Advanced Spectroscopic Methods to Study Biomolecular Structure and Dynamics., Academic Press, USA., Reference Book, 2022
    Role of phenols and polyphenols in plant defense response to biotic and abiotic stresses By Palistha Tuladhar, Santanu Sasidharan and Prakash Saudagar*. in In Fungal Biocontrol Agents and Secondary Metabolites,, Elsevier, Reference Book, 2021
    Culture-Independent Omics-Techniques for Microbiome-Based Molecular Therapeutics Against Infectious Diseases. By Santanu Sasidharan, K. Divakar, and Prakash Saudagar*. in Metagenomic Systems Biology,, Springer, Singapore, Reference Book, 2020
    Understanding Its Role Bioengineered Trichoderma in Managing Soil-Borne Plant Diseases and Its Other Benefits. By Santanu Sasidharan, Palistha Tuladhar, Shweta Raj, and Prakash Saudagar*. in Fungal Biotechnology and Bioengineering, Springer, Singapore, Reference Book, 2020
    Encapsulation and delivery of antiparasitic drugs: a review By Santanu Sasidharan and Prakash Saudagar*. in Encapsulation of Active Molecules and Their Delivery System, Elsevier, Reference Book, 2020
    Virus-like particles: nano-carriers in targeted therapeutics. By Saha, Gundappa, Prakash Saudagar, and Vikash Kumar Dubey. in In Encapsulation of Active Molecules and Their Delivery System, Elsevier, Reference Book, 2020
    An overview of protein/metabolite- based advances in monitoring tools and biosensors: Benefits and application in environmental toxicology. By Santanu Sasidharan and Prakash Saudagar* in In Tools, Techniques and Protocols for Monitoring Environmental Contaminants,, Elsevier, Reference Book, 2019
    Recent advances in the treatment of infectious diseases using nanoparticles By Santanu Sasidharan, Shweta Raj, Prakash Saudagar*. in Recent Trends in Nanobiotechnology: Food and Biomedical Applications,, Central West Publishing, Australia, Reference Book, 2019
    Plant Metabolites as New Leads to Drug Discovery. By Santanu Sasidharan and Prakash Saudagar*. in Natural bio-active compounds, Springer, Singapore, Reference Book, 2019
    Nanomaterial Synthesis: Chemical and Biological Route and Applications. By Santanu Sasidharan, Shweta Raj, Shirish Sonawane, Shriram Sonawane, Dipak Pinjari, A. B. Pandit, and Prakash Saudagar*. in In Nanomaterials Synthesis,, Elsevier, Reference Book, 2019
    Plant cell culture as alternatives to produce secondary metabolites. By Raj, Shweta, and Prakash Saudagar. in In Natural bio-active compounds, Springer, Singapore, Reference Book, 2019
    Patent(s)
    Functionalization Of Carbon Nanotubes With 4’,7-Dihydroxyflavone (Australian Patent number: 2021106369)
    Multiwalled Carbon Nanotubes Functionalized With 4’,7-Dihydroxyflavone as an Anti-Leishmanial Formulation (Indian Patent number:517123)
    PROJECT / CONSULTANCY
    Investigating Universal Min-Circle Sequence Binding Protein (UMSBP) as a Therapeutic Target for Leishmaniasis Drug Development
    Role: Principal Investigator
    Type: Research
    Sponsor: ANRF, Govt. Of India
    Project Cost (INR): 6350000
    Date of Commencement: 26-03-2025  
    Duration: 36 Months
    Status: Ongoing
    Smart polymeric nanoparticles-based delivery system for the delivery of anti-tuberculosis drug
    Role: Co-Principal Investigator
    Type: Research
    Sponsor: SPARC
    Project Cost (INR): 2500000
    Date of Commencement: 28-07-2023   Date of Completion: 31-07-2025
    Duration: 24 Months
    Status: Completed
    Characterization and validation of tyrosine aminotransferase from Leishmania donovani as a potential drug target
    Role: Principal Investigator
    Type: Research
    Sponsor: SERB (DST, Govt. of India)
    Project Cost (INR): 4712000
    Date of Commencement: 10-02-2019   Date of Completion: 28-04-2022
    Duration: 38 Months
    Status: Completed
    Ultrasonic encapsulation of bioactive compounds to deliver in the food matrix
    Role: Co-Principal Investigator
    Type: Research
    Sponsor: DST Indo Russia Bilateral Project
    Project Cost (INR): 1800000
    Date of Commencement: 23-01-2018   Date of Completion: 01-01-2020
    Duration: 24 Months
    Status: Completed
    Studies on Mitogen-activated protein kinase of Leishmania parasite as a therapeutic target
    Role: Principal Investigator
    Type: Research
    Sponsor: SERB (DST, Govt. of India)
    Project Cost (INR): 2090000
    Date of Commencement: 25-01-2015   Date of Completion: 16-04-2018
    Duration: 39 Months
    Status: Completed
    Identification of novel drug candidates for leishmaniasis: Studies on redox enzymes of the parasite
    Role: Principal Investigator
    Type: Research
    Sponsor: Seed Grant, NITW
    Project Cost (INR): 500000
    Date of Commencement: 07-01-2014   Date of Completion: 07-01-2016
    Duration: 24 Months
    Status: Completed
    RESEARCH FELLOWS / PhD STUDENTS
    Current PhD Students
    Arjita Kaushal
    Area of Research: Molecular Biology and Protein Biochemistry of Infectious diseases
    Ch Vihadhar Reddy
    Area of Research: Exploring Drug Target Proteins in Leishmania Parasite
    Gollapalli Seshaveena
    Area of Research: Investigating the role of IDPs in Leishmania Parasite
    Ponnam Chandra Moulika
    Area of Research: Molecular biology and Protein biochemistry of Infectious diseases
    Previous PhD Students
    Santanu Sasidharan (2022)
    Area of Research: Genetic and Chemical Validation of Leishmania Tyrosine aminotransferase as a potential drug target.
    Shital Balasaheb Potdar (2022)
    Area of Research: Extraction and Encapsulation of Bioactive Compounds Using Ultrasound Approach: Parameter Optimization
    Shweta Raj (2020)
    Area of Research: Exploring Leishmanial MAP Kinase as a Therapeutic Target Against Leishmaniasis: Identification and Chemical Validation of Novel Drug Candidates
    PDF Post-Doctoral Fellows
    Banesh Sooram
    Apr 2022 → Apr 2024
    Area of Research: Genetically edited non-pathogenic high capacity adeno viruses as a potential therapeutic agent in Leishmania infection
    CONFERENCE / WORKSHOP / SYMPOSIUM / SHORT TERM COURSE / FACULTY DEVELOPMENT PROGRAMME / GIAN
    Workshop on Fundamentals and current trends on drug delivery system
    11-Nov-2024 → 15-Nov-2024
    Event Type: Workshop
    Role: Co-Principal Investigator
    Funding Agency: SPARC Project
    Greener and Cleaner Ultrasonic Process for Nanomaterials and Nanopharmaceuticals
    27-Jun-2022 → 01-Jul-2022
    Event Type: GIAN Course
    Role: Co-Principal Investigator
    Funding Agency: GIAN project
    Emerging Trends in Biotechnological Advancements: Challenges and Prospects in Tackling Human Diseases
    13-Jul-2020 → 17-Jul-2020
    Event Type: Faculty Development Programme
    Role: Coordinator
    Funding Agency: NIT Warangal
    National Conference on Molecular Biotechnology
    16-Nov-2020 → 19-Nov-2020
    Event Type: Conference
    Role: Coordinator
    Funding Agency: TEQIP-III
    Continuous education program on “Molecular Biotechnology: Tools and Techniques
    22-Oct-2019 → 26-Oct-2019
    Event Type: Short Term Course
    Role: Coordinator
    Funding Agency: NIT Warangal
    Teaching and Learning of Molecular Biology and Enzymology through hands on experience
    18-Sep-2018 → 23-Sep-2018
    Event Type: Workshop
    Role: Coordinator
    Funding Agency: TLC-NITW, PMMMTNMTT, MHRD Govt. of India
    AWARDS AND ACCOLADES
    2025
    Young Scientist Award-2025
    2018
    Young Scientist Award
    Associate Fellow
    2016
    Young Faculty Award
    2015
    Best presentation Award
    2011
    B.S Narasinga Rao Best presentation Award
    ADDITIONAL RESPONSIBILITIES
    •  Member, Project Assessment Panel, MSME Design Scheme (Continuing from August, 2023)
    •  Head, Department of Biotechnology (July, 2023 - June, 2024)
    •  Faculty-in-Charge, M. Tech II-Year (August, 2022 - August, 2023)
    •  Faculty-in-Charge, Department MOUs – Academic & Industry I/c (July, 2019 - July, 2021)
    •  Department NBA coordinator (January, 2019 - January, 2021)
    •  Member, DAC UG (January, 2019 - August, 2021)
    •  Warden IFC-B Mess (November, 2018 - December, 2020)
    •  Faculty-in-Charge, Cell Biology Lab (Continuing from August, 2018)
    •  Faculty-in-Charge, CD-ORD Facility, CIA (August, 2015 - January, 2022)
    •  Member, DAC PG&R (July, 2014 - July, 2017)
    •  Member, DAC UG (July, 2014 - July, 2017)
    •  Faculty in-charge for Time-Table (December, 2013 - December, 2015)
    •  Faculty in-charge for II. B. Tech. (November, 2013 - July, 2017)
    •  Faculty-in-Charge, Molecular Biology & Genetics Lab (October, 2013 - August, 2021)
     Last updated on January 5, 2026